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Background: The impact of gender and aging on relative survival and causes of death in adults with congenital heart disease ACHD are not well known.


Few studies have assessed CKD prevalence among workers in nonagricultural occupations, which was the objective of this investigation.

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Study de: Prospective cohort study. Predictors: Age, sex, education, smoking status, body mass index, alcohol consumption, water consumption, first-degree relative s with CKD, years worked, hours worked per week, job category, study visit baseline and follow-upand self-reported hypertension and diabetes. Analytical approach: A linear mixed-effects model with an unstructured covariance matrix was used to evaluate the association between demographics, occupational risk factors, and eGFR at baseline.

The interaction between risk factors and time with change in eGFR was also evaluated. Multivariable logistic regression models were used to evaluate predictors of CKD. : The CKD prevalence was Linear regression analysis demonstrated ificant predictors of lower kidney function at baseline including oven work, older age, lack of education, and having an immediate family member with CKD.

Predictors of CKD identified using logistic regression analysis included oven work and lack of education. Limitations: Crude job classification measures, loss to follow-up, self-reported exposures. Conclusions: The prevalence of CKD is high in this population of brick workers, suggesting that the epidemic of CKD affecting Mesoamerica is not limited to agricultural workers.

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These are consistent with the hypothesis that occupational heat exposure is a risk factor for kidney disease in this region. Keywords: CKDu; Chronic kidney disease CKD ; Mesoamerican nephropathy MeN ; Nicaragua; brickmaking; disease progression; estimated glomerular filtration rate eGFR ; etiology; heat exposure; heat stress; occupational hazard; risk factor; water consumption.

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Kupferman J, et al. Am J Kidney Dis. Epub Jul 2.

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PMID: Epub Jan Risk factors for reduced glomerular filtration rate in a Nicaraguan community affected by Mesoamerican nephropathy. Raines N, et al. Chicas R, et al.

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Workplace Health Saf. Epub Jun PMID: Review. Yang CW. Epub Sep See all similar articles. Petropoulos ZE, et al.

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An ecological study of chronic kidney disease in five Mesoamerican countries: associations with crop and heat. Hansson E, et al. BMC Public Health. Miller AC, et al. Kidney Int Rep. Pilot study determining the feasibility of implementing the Disadvantaged Populations eGFR Epidemiology Study DEGREE protocol, point-of-care field measurements and a new module on risk factors for chronic kidney disease of unknown origin in Hispanic outdoor workers. Figueroa-Solis E, et al. BMC Nephrol. Sanchez Polo V, et al. Int J Nephrol Renovasc Dis.

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Publication types Research Support, Non-U. Gov't Actions.

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MeSH terms Adolescent Actions. Adult Actions. Female Actions. Humans Actions. Male Actions. Middle Aged Actions. Prevalence Actions.

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